Role of sphingosine kinase-1 in beta cell survival and function.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/529002

Funding Status
Closed

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Funded Activity Summary

Both type 1 and type 2 diabetes remain major health problems in Australia. Although the pancreatic beta-cell death and dysfunction involved in the etiology has been addressed, the mechanisms are still not fully understood. Thus, we seek to establish the role of sphingosine kinase, a strong protector against cell death, in the regulation of beta cell survival and insulin secretion and try to create new therapeutic strategy for the management of diabetes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $85,716.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell death-apoptosis | diabetes | insulin | phospholipids | signal transduction

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