Growth factors and their effect on microRNAs and transcription factors in tubulointerstitial fibrosis in diabetes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/526663

Funding Status
Closed

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Funded Activity Summary

A common cause of kidney disease is diabetes and is partly related to increased expression and action of growth factors such as CTGF. These factors promote the deposition of scar tissue in the kidney by acting on a novel class of intracellular regulator molecules called microRNAs, to change the cell's characteristics such that cells begin laying down excess collagen. This proposal will focus on how growth factors act on microRNAs and the role of microRNAs in diabetic kidney disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $490,202.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology And Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

CTGF | Diabetes | Diabetic Nephropathy | Diabetic complications | EMT | Epithelial mesenchymal transition | Kidney Disease | microRNA

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