Neurogenic hypertension in the spontaneously hypertensive mouse : Role of the hypothalamic-brainstem sympathetic axis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/526662

Funding Status
Closed

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Funded Activity Summary

In human high blood pressure, particularly in the young, an overactive nervous system is thought to be a major underlying cause. Using a unique mouse model of high blood pressure which closely resembles this aspect of the human disease, we will examine which brain cells and neuro- chemicals are involved, particularly in a small area that is involved in regulating the hormonal and nervous system response to stress. From this we hope to be able to target these chemicals with specific therapy.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $475,917.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

CNS angiotensin-oxidative stress | CNS autonomic dysfunction | Hypothalamus and brainstem | arousal associated cardiovascular risk | cardiovascular disease and hypertension | central pathways regulating blood pressure

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