Cytosolic oxidative disturbances as a source of mitochondrial dysfunction in diabetic nephropathy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/526639

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

There is a critical need to identify new therapies for the growing number of patients with diabetic kidney disease. Current medicines only retard progressive disease. Our studies investigate defects in the power houses of the cell, the mitochondria. These defects cause generation of toxic free oxygen radicals which eventually starve the cell of energy production. Therefore, reversal of mitochondrial defects in diabetic kidney disease may be a novel therapeutic target.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $505,786.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology And Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

NADPH oxidase | diabetes | diabetic complications | diabetic nephropathy | glycation | mitochondrial respiratory chain | nephropathy

Related Links