The organisation of the chromosome into distinct epigenetic domains and its link with development and disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/525424

Funding Status
Closed

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Funded Activity Summary

This investigation will show that a key cellular mechanism that determines how the chromosome is organised into stable domains is by changing the make-up of chromosomal domains through the replacement of histone proteins with specialised forms of histones called variants . This fundamental research will provide important new information on how chromosomes become unstable in cancer.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $521,591.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Aging | Cancer | Centromere | Chromatin structure | Chromosome instability | Chromosomes | Epigenetics | Histone variants

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