Investigating the role of TCR avidity in Influenza virus-specific CD8 T cell responses

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/520643

Funding Status
Closed

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Funded Activity Summary

One of the constituents of the immune system is the cytotoxic, or killer, T cells and these are important in the overall protection from viral infection. Activation of these T cells is mediated by signalling through the T cell receptor (TCR). This study will definitively determine how the strength with which the TCR binds to the activating ligand, can influence the quality of virus-specific T cell immune responses after infection. This has implications for vaccine design.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2013

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $83,142.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell mediated immunity | Cytotoxic T cell | Retroviral transduction | T cell immunity | Viral immunity

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