Effects of parvalbumin up-regulation on Ca2+ handling and contractile properties in skeletal muscle from aged mice

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/520186

Funding Status
Closed

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Funded Activity Summary

Ageing is accompanied by a loss of muscle function that may be due to an ageing-related impairment of calcium regulation. This project aims to improve calcium regulation in muscles of aged animals by enhancing the calcium buffering capacity via gene transfer. Whether this improves muscle function and muscle regeneration following injury in the aged will be assessed. Information from this project could lead to development of novel strategies to combat the loss of muscle function with ageing.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: Early Career Fellowships

Funding Amount: $287,321.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biotechnology diagnostics (incl. biosensors)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ageing | Calcium | Skeletal muscle

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