Understanding G Protein-Coupled Receptors (GPCRs): Accelerating Discovery from Concept to Clinic.

Funding Activity

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Funded Activity Summary

G Protein-Coupled Receptors (GPCRs) form the largest family of receptors (and thus drug targets) in living organisms. Currently, the major reason that new drugs fail to reach the clinic is lack of appropriate drug effect (approx. 30%). Thus, we need a better understanding of how GPCRs work and how this relates to disease. Our Program addresses this knowledge gap, using GPCR models that are relevant to treatment of metabolic, cardiovascular and central nervous system disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2013

Funding Scheme: Programs

Funding Amount: $6,871,789.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptor | drug target validation | ligand binding | molecular pharmacology | receptor activation and cell signalling