STIM1 and Orai1 proteins in store-operated calcium entry in liver

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/519115

Funding Status
Closed

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Funded Activity Summary

The liver plays a central role in controlling vital functions of the body. Changes in calcium level in the liver cells regulate most their functions, including fat and carbohydrate metabolism. There is ample evidence that suggests that diseases such as fatty liver and cholestasis affect the control of calcium in the liver. This research will investigate the mechanisms of calcium homeostasis in the liver and provide information for development of new approaches for treating liver disease.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $516,552.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biotechnology diagnostics (incl. biosensors)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell signalling | Diabetes complications | Ion channel dysfunction | Liver diseases | Molecular basis of disease | calcium channels | calcium imaging | confocal microscopy | patch clamping | protein-protein interaction

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