Identification of cancer initiating cells in small-cell lung cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/516781

Funding Status
Closed

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Funded Activity Summary

Lung cancer is the leading cause of cancer deaths worldwide. Recently a unique mouse model of small-cell lung cancer (SCLC) has been generated that closely mimics the human disease. We will use this model to identify the cells that give rise to SCLC upon genetic alteration. Results obtained will assist in designing more effective intervention strategies aimed at overcoming initial and acquired resistance of these tumours against cytotoxic and targeted drugs.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2015

Funding Scheme: Early Career Fellowships

Funding Amount: $364,420.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Genetics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

conditional gene targeting | murine models | small-cell lung cancer | stem cells | targeted therapy

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