Trafficking and expression of PfEMP1 on the surface of P.falciparum-infected erythrocytes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/516739

Funding Status
Closed

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Funded Activity Summary

Malaria causes over 2 million deaths each year. The parasite infects human red blood cells and expresses a virulence protein on the erythrocyte surface allowing it to adhere to the microcapillaries preventing clearance through the spleen. We aim to understand how the parasite is able to express this virulence protein on the parasite-infected red blood cell surface. Identification of the proteins involved will provide potential drug targets to develop novel antimalarial compounds and strategies.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $558,189.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Basis of disease in falciparum malaria | Cell adhesion | Immunity | Malaria in pregnancy | Plasmodium falciparum malaria | Protection against malarial disease

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