Identification of novel regulators of Flt3 receptor-dependent dendritic cell development and differentiation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/516724

Funding Status
Closed

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Funded Activity Summary

Dendritic cells are specialized immune cells that play a key role in regulating the immune system. In the resting animal, their differentiation is largely regulated by signalling though the Flt3 pathway - the pathway most frequently dysregulated in leukemias. This project will generate a a detailed map of the important signals that instruct dendritic cell development along the Flt3 pathway and provide improved understanding of the cellular and molecular controls of this pathway.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $605,043.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cancer | Leukemia | Neoplasia | cell development | dendritic cells | transcription

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