Mitochondrial chaperones: Import of membrane-spanning precursors through the inter-membrane space

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/516713

Funding Status
Closed

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Funded Activity Summary

All cellular proteins are made on ribosomes. Highly regulated transport systems then move them about the cell. Specialised 'translocases' mediate import of proteins to the mitochondria. This project focuses on how translocase components recognise, target, and transfer their charges; in particular, on the import of a class of solute carriers that insert into the inner mitochondrial membrane.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $328,194.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Membrane transport | Mitochondria | Transmembrane protein | X-ray crystallography | mis-targeting of proteins to organelles | mitochondrial myopathies | neurodegenerative and age-related diseases

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