Defining the mechanism of invasive disease caused by diverse group A streptococcal M serotypes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/514639

Funding Status
Closed

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Funded Activity Summary

Streptococcus pyogenes (group A Streptococcus; GAS) causes life-threatening invasive infections including flesh-eating disease and toxic shock syndrome (>600,000 cases and 163,000 deaths per year). We recently discovered the trigger for invasive disease in a globally disseminated GAS strain. The aim of this work is to determine whether this trigger applies to other strains associated with GAS invasive disease. These studies will allow the development of new therapeutics and treatments.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: Early Career Fellowships

Funding Amount: $393,061.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacterial genetics | Bacterial pathogen | Plasminogen | Streptococcus | Streptodornase

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