A Stable Protein:DNA Complex for Development of Ultrasensitive Diagnostics in Multiplex Format

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/514605

Funding Status
Closed

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Funded Activity Summary

A new technology platform will be developed to carry out diagnostic tests in a multiplex format with increased sensitivity and precision. We recently discovered a very strong interaction between a protein and a particular fragment of DNA. This interaction can be tuned to enable its use for the simultaneous detection of different disease markers in a single assay. This will improve the time and space needed to perform diagnostic tests in laboratories.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $521,961.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Diagnostic Applications

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA binding protein | X-ray crystallography | diagnostic methods | early detection of cancer | early diagnosis | immunodiagnostic technique | infectious diseases | molecular diagnostics | protein engineering | quantitative real-time PCR

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