Mechanisms underlying growth, lineage commitment and differentiation of liver progenitor cells

Funding Activity

Website
http://grants.uberresearch.com/501100000925/http://purl.org/au-research/grants/nhmrc/513896/How-do-liver-stem-cells-grow-and-develop-into-functional-liver-cells

Funding Status
Closed

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Funded Activity Summary

Liver disease is a serious health problem. Viral hepatitis, obesity and alcohol can result in end-stage liver disease. Organ transplant is the only treatment available. A widening gap between organ donations and recipients mandates alternative treatments are developed. Cell transplantation and artificial liver devices are alternatives which can use liver progenitor cells. We will investigate how factors grow and convert them into liver cells for treating liver disease patients.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $535,333.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

cell therapy | chronic liver disease | hepatocytes and cholangiocytes | inflammatory cytokines | liver cell lineage commitment | liver progenitor cells | stem cells | viral hepatitis, HBV and HCV

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