Functional role of a novel coregulator in metabolism

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/513813

Funding Status
Closed

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Funded Activity Summary

Australia is facing a massive epidemic of diabetes and obesity (diabesity). These disorders afflict all age groups, including teenagers, and are a major burden to the health and wealth of Australia. The nuclear receptors and their coregulators are excellent targets for developing new therapeutics to combat these disorders. This grant will evaluate the functional role of SLIRP, a novel nuclear receptor coregulator, in metabolism and could provide new avenues for drug target development.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $563,146.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Adipose, muscle and fat cell metabolism | Combinatorial approach to improving insulin resistance | Coregulators and hormone action | Developing new ways to treat type 2 diabetes and obesity | Insulin resistance, diabetes, lipids and energy metabolism | Mitochondrial biology | Role of novel coregulators in lipid and energy metabolism | SLIRP, PPARs and thiazolidinediones | Understanding hormone signaling in fat and muscle cells

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