Regulation of the androgen signaling pathway in prostate cancer by microRNAs

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/513808

Funding Status
Closed

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Funded Activity Summary

Prostate cancer is the most common cancer in men and is dependent upon signaling from male hormones (androgens) for continued growth. We recently identified some novel small RNAs (intracellular messengers), called microRNAs, that are likley to play important roles in maintaining the androgen signaling pathway in prostate cancer. This project will evaluate the functional role of these microRNAs in human prostate cancer, and may provide the foundation for new avenues for therapeutic intervention.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $540,075.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endodontics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Androgen receptor signaling pathway | Androgen resistant prostate cancer | Combined miRNA and chemotherapy treatment in prostate cancer | Dicer, TRBP and PACT | Prostate cancer | Receptor tyrosine kinase signaling | Role of microRNAs in human prostate cancer growth | microRNAs and RNA metabolism | microRNAs as potential therapeutics in prostate cancer

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