Development of resonance energy transfer technologies to detect GPCR heterodimer complexes in living cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/513780

Funding Status
Closed

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Funded Activity Summary

G-protein coupled receptors are proteins at the surface of most cells in the body. They bind to drugs, transmitting signals into cells that change what cells are doing. Recent research indicates that different types of these proteins can interact with each other and when one of these protein combinations binds a drug, it acts differently to when the proteins act separately. The aim of our project is to find out which protein combinations exist and to find drugs that bind to them specifically.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2009

Funding Scheme: NHMRC Development Grants

Funding Amount: $205,555.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Assay development | Bioluminescence resonance energy transfer (BRET) | Drug Discovery | Endocrine Diseases | Pharmaceutical development | Protein-protien interaction | Proteomics | Pulmonary Disease

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