A preclinical model of relapse in acute lymphoblastic leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/513765

Funding Status
Closed

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Funded Activity Summary

Leukaemia is the most common type of cancer in children but resistance to therapy continues to be a significant problem. This project will investigate the biology of drug-resistance and relapse using a mouse model that replicates the human disease. We hope to identify novel therapeutic targets that can be used in combination with existing therapies to improve outcomes in this disease. We also hope to identify markers that can be used to screen for patients at increased risk of relapse.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $573,515.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drug resistance | Drug resistant leukaemia | Gene expression | Leukaemia | NOD-SCID mouse model | Novel anti-cancer agents | Paediatric acute lymphoblastic leukaemia | Relapse

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