Determinants of immune restoration disease and persistent immune dysfunction in HIV patients responding to ART

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/513755

Funding Status
Closed

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Funded Activity Summary

Many people throughout the world now receive antiretroviral treatment (ART) for HIV-AIDS. ART increases numbers of CD4 T-cells, but does not restore all functions the immune system. In addition, some patients experience serious exacerbations of pre-existing secondary infections when they respond to ART. We were the first to describe these Immune Restoration Diseases and will investigate the underlying mechanisms and the causes of persistent immune deficiency here.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $445,011.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

HIV pathogenesis | HIV related immune suppression | HIV-AIDS | T cell immunity | combination antiretroviral therapy | cytokine regulation | herpes | immunogenetics | immunopathology | pulmonary tuberculosis

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