Molecular mechanism and novel activators of amino acid and calcium-sensing class 3 G-protein coupled receptors

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512546

Funding Status
Closed

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Funded Activity Summary

When we eat protein-containing foods, our bodies extract twenty different amino acids for growth and tissue regeneration. Broad-spectrum amino acid sensing receptors detect the increases in blood amino acid levels and respond by triggering the release of biochemical signals. This project will establish the molecular rules by which these receptors work and identify novel activators with potential therapeutic application for the control of growth, tissue regeneration and calcium metabolism.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $519,715.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G-protein coupled receptor | Venus Fly Trap | amino acid sensing | extracellular calcium | impact of amino acids on hormone secretion | impact of dietary protein on growth and metabolism | impact of dietary protein on tissue maintenance | intracellular signalling | therapeutics that target amino acid sensing mechanisms

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