Immunopathological role of monocyte-macrophages in flavivirus encephalitis.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512413

Funding Status
Closed

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Funded Activity Summary

Viral encephalitis is a life-threatening infection of the brain for which there are no reliable treatments. White cells called monocytes enter the brain from the blood and although important in the immune response that destroys the virus, can also damage the brain. Our work focuses on determining how monocytes migrate into the brain in viral infection, what functions they have once inside the brain, and how to exclude a certain types of monocytes that we have found to be particularly damaging.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $445,011.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Antiviral immunity | Cell Migration | Chemokine | Flavivirus encephalitis | Immunopathology | Innate immunity | Neuroimmunology | Neuroinflammation | Regulation of Immune Response | Viral Immunity

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