Role of GAT-1 transporter channels in opioid dependence

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512390

Funding Status
Closed

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Funded Activity Summary

Opioid drugs including heroin and morphine are very addictive. After cessation of chronic use of these drugs an intensely unpleasant withdrawal syndrome develops that contributes to relapse. Brain mechanisms that produce withdrawal are still poorly understood. The present work will determine the pathological cellular and molecular mechanisms that produce withdrawal in inhibitory brain nerve cells known to be involved in generating withdrawal discomfort and relapse to compulsive drug use.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $524,456.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

addiction | central nervous system | neuropharmacology | neurophysiology | neurotransmitters | opioid dependence | opioid pharmacology | opioid tolerance | transporters

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