Signal transduction in airway remodelling

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512301

Funding Status
Closed

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Funded Activity Summary

In the asthmatic lung structural changes, such as increased deposition of proteins which form the scaffolding of the airways (the extracellular matrix proteins), and an increased mass of bronchial smooth muscle cells occur. Many of these critical structural changes are not reversed or prevented with current asthma therapy, thus we need to investigate, by using lung cells and tissues , why they happen and how we can prevent them.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $626,141.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Airway fibrosis | Asthma | Chronic obstructive pulmonary disease | Lung function | PI3 kinase | airway inflammation and remodelling | airway remodelling | airway smooth muscle fibroblasts epithelial cells | phosphodiesterase | signal transduction

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