Activated protein C utilises protease activated receptors and epidermal growth factor receptor to heal wounds

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512179

Funding Status
Closed

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Funded Activity Summary

Chronic leg ulcers are a major burden to the individual sufferer and to the health system. We have discovered that activated protein C (APC) potently stimulates wound healing in the laboratory and now have exciting positive results from a small pilot clinical trial showing that applying APC solution to leg ulcers also helps healing in patients. This study plans to discover how APC works at the molecular level.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $436,882.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

delayed wound repair | protease | skin | therapeutic agent | topical drug delivery | wound healing

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