Characterisation of the pathways leading to DNA demethylation in the embryo.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512147

Funding Status
Closed

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Funded Activity Summary

Complex living creatures like humans have specialised cells that co-operate to form important organs like brains and reproductive organs. Specialised cells have specific genes locked on or off. When a sperm fertilises an egg, all the switches of the genes that are locked on or off get reset to neutral so that the fertilised egg can divide and grow into all cell types in the body. We do not know how this resetting happens in the egg. This project seeks to discover the mechanism involved.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $634,573.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | DNA repair | assisted reproductive technology | defects in embryonic development | embryo | epigenetics | human embryo development, embryo stem cells and cancer | in vitro fertilization | loss of imprinting | preimplantation embryology

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