Investigating the potential effect of a novel immune regulator (JET) in preventing Graft Versus Host Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/512003

Funding Status
Closed

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Funded Activity Summary

Graft Versus Host Disease (GVHD) is the primary complication of bone marrow transplants, in which the donor T-cells react with the recipient’s cells causing organ damage. Current treatments are not specific and cause further health problems. This research aims to test the therapeutic potential of a newly discovered molecule (JET) in treating and preventing GVHD. If successful, JET has the potential for treating other conditions such as rheumatoid arthritis, multiple sclerosis and miscarriages.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $82,895.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ets-1 | Graft Versus Host Disease | T-bet | Th1 immune responses

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