The Molecular Function and Role of The New Metastasis Suppressor NDRG1 in Cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511988

Funding Status
Closed

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Funded Activity Summary

With cancer now a leading cause of death in Australia, finding new ways to treat this disease is crucial. Iron is critical for cancer cell growth and metastasis, thus agents that bind iron (called iron chelators) can be used to treat cancer. These drugs up-regulate the gene NDRG1, which has been shown to prevent tumour spread. The role of NDRG1 in tumour growth and spread of cancer cells will be examined as this may lead to novel therapies against cancer (e.g. the use of novel iron chelators).

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: Early Career Fellowships

Funding Amount: $226,425.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

metastases | molecular biology | transcriptional regulation | tumour suppressor gene

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