Molecular pathways mediating quiescence and resistance in leukaemia stem cells in acute myeloid leukaemia.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511275

Funding Status
Closed

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Funded Activity Summary

Acute myeloid leukaemia (AML) is a devastating cancer of the blood and bone marrow which is rapidly fatal unless effectively treated with chemotherapy. AML is caused by genetic events that alter normal blood stem cells to give them a growth and survival advantage and also may confer resistance to chemotherapy in some cases. We will evaluate and target the mechanism of this resistance in laboratory models. This information can then be used to design new treatments to improve outcomes in AML.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $100,381.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute myeloid leukaemia | Leukaemia stem cells | Oxidative stress

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