Inhibition of histidine kinase signal sensing: a novel paradigm for antimicrobial development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511206

Funding Status
Closed

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Funded Activity Summary

Staphylococcus aureus (Golden staph) has been termed a superbug because of its remarkable ability to acquire resistance to virtually all antibiotics. Until recently, Golden Staph infections were almost always acquired in hospitals, but the increasing incidence of community-acquired S. aureus infections has rendered it a major public health threat in Australia. The aim of this research is to develop antimicrobial agents to combat antibiotic-resistant strains of Staphylococcus aureus.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $464,144.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Staphylococcus aureus | X-ray crystallography | antibiotics | infectious disease | multiply-resistant staphylococci | nosocomial infections | nuclear magnetic resonance (NMR) | protein structure | staphylococcus | two-component signal transduction

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