Preserving barriers: how cadherin signaling coordinates dynamic adhesion and tight junction assembly in epithelial cell.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511156

Funding Status
Closed

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Funded Activity Summary

Epithelia protect the body from its environment. Breakdown of the epithelial barrier in tissues such as the skin and intestine, as occurs in burns and inflammation, leads to invasion of bacteria and severe metabolic disturbances. In this project we study the cell signaling mechanisms that maintain epithelial barriers in healthy tissues that undergo turnover and remodelling. Understanding these signaling pathways provides a foundation to understand how they are perturbed in disease.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $557,939.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cancer Biology | Cell Adhesion | Cell Biology | Cell signaling | Cytoskeleton | Epithelial Biology | Invasion | Metastasis

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