Investigation into the alternative splicing of steroid hormone regulated genes in breast cancer.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/511153

Funding Status
Closed

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Funded Activity Summary

Steroid hormones have imortant roles in breast tissue growth and differentiation. We have identified several proteins called PRMT6 and CAPER's , that are involved in steroid hormone signaling and control the alternative splicing of RNA, the process in which several different proteins can be produced from a single gene. Our aim is to study these proteins in an effort to understand how they influence alternative splicing and to identify genes they control in relation to breast cancer.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $292,216.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Biochemistry and molecular biology | Cancer biology | Control of gene Expression | Gene expression | Molecular Mechanisms | RNA binding proteins | RNA processing | Steroid hormone receptors | post-transcriptional regulation of gene expression | steroid hormone action

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