Store operated Ca2+ entry in skeletal fibres from normal and dystrophin-deficient muscle.

Funding Activity

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Funded Activity Summary

Skeletal muscle, the most abundant tissue in the body, is essential for life and movement. Muscle function is regulated in a complex manner by calcium and is severely impaired in patients with Duchenne muscular dystrophy. Changes in calcium regulation, known to occur in dystrophic muscle, will be investigated in an animal model using a novel, single cell approach. Results obtained will contribute to understanding better muscular dystrophy and help provide therapeutic targets for treatment.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $351,790.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biotechnology diagnostics (incl. biosensors)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium imaging | mechanically skinned fibres | muscle | muscular dystrophy | musculoskeletal physiology | physiology

ACN 633 798 857