Pneumovirus infection in infancy affects the development of life-long adaptive immunity.

Funding Activity

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Funded Activity Summary

Respiratory syncytial virus is the most important cause of acute lower respiratory tract infection (RTI) in young children worldwide. Hospital admission rates in Western societies for RTIs are around 3% for children younger than 1 year. A vaccine to RSV is not yet available and repeat infections occur thoughout life, suggesting that the immune response does not develop correctly. In this project we are exploring the mechanisms that underpin disease development and promote incomplete immunity.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $408,469.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Acute and chronic lung infections | Airway inflammation | Asthma and COPD | Innate immunity | Neonatal-pediatric respiratory diseases | Neutrophils | Respiratory diseases | Respiratory syncytial virus | Viral bronchiolitis