The mechanisms underlying pneumoviral-induced angiogenesis of the lung and its impact on the asthmatic response.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510715

Funding Status
Closed

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Funded Activity Summary

Asthma, is a serious respiratory disease resulting in structural changes to the lung and breathing difficulties, and is often compounded by respiratory viruses. We have shown that viral infection of newborn mice causes the growth of new blood vessels in the lungs (a feature seen in human asthmatics). This project will investigate the mechanisms involved and determine the potential of this feature as a therapeutic target.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $564,625.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Acute and chronic asthma | Airway inflammation and remodelling | Airway remodelling | Angiogenesis | Asthma | Asthma and allergy | Chronic inflammation | Respiratory viral infection | Respiratory viruses

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