Tissue factor de-encryption in vivo

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510423

Funding Status
Closed

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Funded Activity Summary

Blood clotting in the wrong place at the wrong time is responsible for up to 50% of the morbidity and mortality of the population through diseases such as heart attack, stroke, venous thrombosis. It also contributes to cancer progression and cancer related death. Blood clotting is initiated when a protein on the cell surface known as tissue factor becomes active. We will determine how activation of tissue factor participates in the blood clotting process. This will help in disease prevention.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2013

Funding Scheme: Early Career Fellowships

Funding Amount: $415,046.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Disulfide bonds | Endothelial cells | Protein oxidation | Thiol isomerisation | Tissue factor

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