Molecular regulation of replicative lifespan; implications in carcinogenesis and haematopoiesis

Funding Activity

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Funded Activity Summary

The lifespan of normal cells in the body is limited by the number of times they can replicate. In contrast, cancer cells can replicate indefinitely – they are immortal. Our proposed investigations will determine how the mechanisms that control cell lifespan become dysfunctional as normal cells evolve into cancer cells. Understanding these mechanisms will enable the development of new anti-cancer drugs that will reverse cell immortality and halt the replication of cancer cells.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: Career Development Fellowships

Funding Amount: $420,872.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Carcinogenesis | Erythropoiesis | Immortalisation | Senescence | Telomeres