Expression and functions of leukocyte Immunoglobulin-like Receptor (LIR)-6 and LIR-4 in inflammatory arthritis (IA).

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510236

Funding Status
Closed

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Funded Activity Summary

Rheumatoid arthritis (RA) that affects millions worldwide is characterised by uncontrolled activation of immune cells destroying ones own joints. The reasons for this excessive activation of cells are not known and existing treatments are limited to easing symptoms. We will study the role of new proteins named as Leucocyte Ig-like Receptors in regulating immune cell activation. Understanding mechanisms that control unwanted activation of immune cells is critical in preventing and treating RA.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $292,216.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Emergency medicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Immune regulation | Inflammation | autoimmune diseases | autoimmunity | chronic Inflammation | rheumatoid arthritis

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