Membrane order at T cell activation sites

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510225

Funding Status
Closed

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Funded Activity Summary

The activation of T lymphocytes is essential part of our immune system to fend off harmful intruders. Our research aims to understand the process of T cell activation, in particular, the contribution of fats. We found that fats create a highly ordered patch at the T cell activation site. We want to understand how lipids and proteins work together to activate T cells, how this ordered regions function in T cell activation and whether dietary lipids alter these patches and thus T cell activation.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $519,715.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell signalling | Hyperlipidemia | Lipid rafts | Lipids | Membrane structure | Molecular basis of disease | Regulation of immune responses | Signal transduction | T lymphocytes

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