Cellular changes due to LRRK2 parkinsonism

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510186

Funding Status
Closed

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Funded Activity Summary

Parkinson's disease is a progressive, disabling, age-associated neurological disorder with no known cure. Several genes have been identified as causing Parkinson's disease, although mutations in leucine-rich repeat kinase2 (LRRK2) are by far the most common. The studies we propose will identify the cellular proteins that interact with LRRK2 to cause Parkinson's disease. These proteins may be amenable to future therapeutic manipulation.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $631,227.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology And Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Parkinson's disease | genetics | inherited diseases | molecular basis of disease | neurodegeneration | neurodegenerative and age-related diseases | pathogenesis | proteomics | transcription

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