Transcriptional regulation of haematopoietic stem cell development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/510100

Funding Status
Closed

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Funded Activity Summary

Cancer initiating cells acquire stem cell characteristics and self renew within a supportive environment that helps maintain and propagate malignant tumours. Identifying the normal hierarchy of gene regulation within blood stem cells and designing therapies that target key transcription factors (proteins that control other genes) that are over expressed in cancer stem cells is the ultimate goal.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $566,470.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cancer Stem cells | Cell signalling | Gene regulation | Haematopoietic stem cells | Leukaemia and Cancer | Myelo and lymphoproliferative disorders | Stem cell niche | Tissue regeneration | Transcriptional networks

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