Competition for polarity influences lymphocyte differentiation and function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509358

Funding Status
Closed

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Funded Activity Summary

CD46 is a protein on human cells that viruses and bacteria bind to during infection. Our laboratory has found that binding of CD46 on immune cells impairs their ability to recognize and kill target cells and may explain the immunosuppression caused by measles infection. We aim to investigate the mechanisms behind the effect of CD46 on immune cells. The outcomes of this study will define new paradigms in lymphocyte biology and determine how CD46 influences the immune response to infection.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: Career Development Fellowships

Funding Amount: $380,558.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell divisions | Immunoregulation | Lymphocyte | Lymphocyte differentiation | Viral immunity

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