Astrocytic glutamate transporters: molecular characteristics of their activity-dependent localization and targeting

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509319

Funding Status
Closed

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Funded Activity Summary

Dysfunction of glutamate transport is implicated in the pathology of neurodegenerative conditions. Our aim is to understand how the molecules responsible for glutamate transport are organized on the cell surface and how their movement within cells regulates transporter activity. Advances of this type will indicate new pharmacological and molecular biological strategies for the management of brain disorders.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $558,189.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

astrocytes | cell culture | excitatory amino acids | glutamate metabolism | membrane transport | molecular pharmacology | neurodegeneration | neuroinflammation | protein trafficking | therapeutic target

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