Dicer1 gene in mammalian gametogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509311

Funding Status
Closed

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Funded Activity Summary

We propose to determine if a recently discovered biological mechanism plays crucial roles in the development of eggs and sperm. To achieve this, we will remove or mutate this pathway specifically in developing eggs and sperm , then examine the effect. Preliminary results indicate that the mechanism does play important roles mutated eggs fail to complete maturation. These studies will tell us more about what makes a healthy egg and sperm, and are relevant to female and male fertility.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $499,166.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA metabolism | assisted reproductive technology | female infertility | gametocytogenesis | gametogenesis | germ cells | in vitro maturation of oocytes | male infertility | reproduction | reproductive health

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