Role of L1CAM in enteric nervous system development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509219

Funding Status
Closed

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Funded Activity Summary

There are millions of nerve cells in the gut. During development, these nerve cells arise from cells (neural crest) that migrate from the developing brain. Neural crest cells migrate into and along the gut. Some humans have a condition called Hirschsprung's disease in which nerve cells are absent from parts of the gut. Afflicted individuals have severe constipation and require surgery. In this study, we will identify the mechanisms controlling neural crest migration in the developing gut.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $374,759.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Hirschsprung's disease | cell migration | congenital disorders | development | enteric nervous system | gastroenterology | motility disorders | neural crest | neural crest cell lineage | neuronal differentiation

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