Regulation of PML by E6AP: implications for tumour development.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509196

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

PML is a vital tumour suppressor, but little is known about its regulation. We established that PML levels are affected by another cellular protein E6AP. This study will define the mechanism by which E6AP influences PML. Human cancers will be screened for the involvement of these proteins, to gain new insights into cancer onset. The intended practical outcome of these studies is to aid cancer diagnosis and provide new anti-cancer drugs.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $537,829.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

E6AP | PML | cancer | cancer biology | mechanisms inhibiting cancer cell growth | tumour suppressor | ubiquitin-mediated proteolysis

Related Links