Probing developmental causes of soft tooth enamel with novel mouse models

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509171

Funding Status
Closed

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Funded Activity Summary

Tooth decay is one of the most costly diseases in Australia and was recently called a national tragedy by the Prime Minister. The risk of decay increases if teeth don't harden properly in childhood. This project aims to clarify the causes of soft enamel and identify ways to prevent it. Two new test systems will be used to see how antibiotics and fluoride affect enamel hardening. Our findings will help the battle against tooth decay and guide the safe use of medicines in children.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $470,112.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cellular causes of DDE and safety of paediatric medicines | Cytotoxicity | Dental development | Disease models, animal | Fluoride safety and prevention of dental fluorosis | Intracellular calcium | Murine models | Tooth wear prevention

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