The role of Snail family proteins in stem cells and tumour growth

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509158

Funding Status
Closed

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Funded Activity Summary

This project investigates the role of a family of genes in regulating stem cells in normal tissues and cancer. This family can switch other genes off and we hypothesize that keeping these genes off is required to allow stem cells to be maintained in tissues. We combine novel studies in fruit flies and mice to examine gene function in stem cells and tumour initiation. These studies will increase our knowledge of how to manipulate stem cells and may identify new targets for tumour therapy.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $589,175.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drosophila | cancer: mechanisms of growth, invasion, metastases | genetic predisposition to disease | mechanisms inhibiting cancer cell growth | mouse genetics | stem cells | stem cells as gene therapy targets | transcriptional regulation | tumour suppressor

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