The structural basis of the interaction of insulin-like peptide 3, a key regulator of fertility, with its receptor.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/509048

Funding Status
Closed

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Funded Activity Summary

The hormone, insulin-like peptide 3, has recently been shown to act directly on male and female germ cells to cause their maturation. It has considerable promise as a therapeutic agent for the regulation of fertility. Drugs based on the peptide may be used to assist in cases of infertility, and drugs that block its action have great potential as male and female contraceptives. Towards these goals, our project aims to understand how this peptide exerts its unique biological effects.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $555,693.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

contraception | cryptorchidism | drug design | drug development | fertility | fertility-infertility | insulin-like peptide 3 | male contraception | molecular pharmacology | structure-activity relationships

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